Inclusion or equity in digital educational contexts requires a purposeful design that makes the most of the opportunities and overcomes potential challenges associated with the use of technology, paying particular attention to the challenges affecting underserved students. This requires a new pedagogy and this handbook seeks to empower teachers with skills for inclusive digital education in online, blended, and hybrid learning environments. The knowledge developed in this project is also distributed through e-learning modules for teachers, an Awareness Raising Tool, and the e-Inclusion course, piloted at the Universitat Oberta de Catalunya in 2022.